Department of Biomedical Informatics
Department of Pathology
Stony Brook, NY 11794
Phone: (631) 638-2271
Bioinformatics, personalized medicine, pancreatic adenocarcinoma, mixture modeling.
Dr. Moffitt Received his B.S. and Ph.D. from the department of Biomedical engineering at Georgia Tech and Emory University, and completed his postdoctoral research in the Lineberger Cancer Center at the University of North Carolina. He Joined the BMI department at Stony Brook in 2017.
The Moffitt lab uses bioinformatics and engineering approaches to improve scientific understanding and to advance patient care in cancer, with a focus on pancreatic adenocarcinoma. Dr. Moffitt’s current research projects include:
- Predictive models in pancreatic adenocarcinoma, with a focus on precision medicine and patient response to therapy.
- Mixture modeling and next generation sequencing techniques to study tumor, stromal and immune contributions to tumor biology
- Translational bioinformatics and biostatistics methods development for tumor biology and medical data.
- SELECTED PUBLICATIONS:
- Virtual microdissection identifies distinct tumor-and stroma-specific subtypes of pancreatic ductal adenocarcinoma
RA Moffitt, R Marayati, EL Flate, KE Volmar, SGH Loeza, KA Hoadley, ...
2015, Nature genetics 47 (10), 1168-1178
- Integrated Genomic Characterization of Pancreatic Ductal Adenocarcinoma Cancer Genome Atlas Research Network
2017, Cancer Cell 32 (2), 185-203. e13
- Comprehensive Pan-Genomic Characterization of Adrenocortical Carcinoma
S Zheng, AD Cherniack, N Dewal, RA Moffitt, L Danilova, BA Murray, ...
2016, Cancer Cell 29 (5), 723-736
- Genomics-Driven Precision Medicine for Advanced Pancreatic Cancer: Early Results from the COMPASS Trial
KL Aung et al.
2018, Clinical Cancer Research 24 (6), 1344-54
BMI502: Life Science for Biomedical Informatics
BMI560: Personalized Medicine