Richard Moffitt


Richard Moffitt     
Assistant Professor & Graduate Program Director,
Department of Biomedical Informatics
Stony Brook Cancer Center
Department of Pathology
Department of Pharmacological Sciences
HSC L3-045G
Stony Brook, NY 11794
Phone: (631) 638-2271
Bioinformatics, personalized medicine, pancreatic adenocarcinoma, mixture modeling, COVID-19 electronic heath record analytics.
Dr. Moffitt received his B.S. and Ph.D. from the Department of Biomedical Engineering at Georgia Tech and Emory University, and completed his postdoctoral research in the Lineberger Cancer Center at the University of North Carolina. He joined the BMI department at Stony Brook University in 2017.
The Moffitt lab uses bioinformatics and engineering approaches to improve scientific understanding and patient care, with a focus on pancreatic adenocarcinoma and COVID-19. Dr. Moffitt’s current research
projects include:
  • Predictive models in pancreatic adenocarcinoma, with a focus on precision medicine and patient response to therapy.
  • Mixture modeling and next generation sequencing techniques to study tumor, stromal and immune contributions to tumor biology
  • Translational bioinformatics and biostatistics methods development for tumor biology and medical data.

Clinical Characterization and Prediction of Clinical Severity of SARS-CoV-2 Infection Among US Adults Using Data From the US National COVID Cohort Collaborative
TD Bennett, RA Moffitt, JG Hajagos, B Amor, A Anand, MM Bissell, ...
2021, JAMA Network Open 4 (7), e2116901-e2116901

Purity Independent Subtyping of Tumors (PurIST), A Clinically Robust, Single-sample Classifier for Tumor Subtyping in Pancreatic Cancer
NU Rashid, XL Peng, C Jin, RA Moffitt, KE Volmar, BA Belt, RZ Panni, ...
2020, Clinical Cancer Research 26 (1), 82-92

Real-time genomic characterization of advanced pancreatic cancer to enable precision medicine
AJ Aguirre, JA Nowak, ND Camarda, RA Moffitt, AA Ghazani, ...
2018, Cancer discovery 8 (9), 1096-1111

Integrated Genomic Characterization of Pancreatic Ductal Adenocarcinoma Cancer Genome Atlas Research Network
2017, Cancer Cell 32 (2), 185-203. E13

Virtual microdissection identifies distinct tumor-and stroma-specific subtypes of pancreatic ductal adenocarcinoma
RA Moffitt, R Marayati, EL Flate, KE Volmar, SGH Loeza, KA Hoadley, ...
2015, Nature genetics 47 (10), 1168-117

Course Director:
BMI517 Current Research in Signaling Pathways, Biochemistry, and Tissue Morphology of Disease
BMI530 Software Development in Biomedical Informatics, cross-listed as part of the Vertically Integrated Projects program

Lectures in:
BMI502 Life Science for Biomedical Informatics
BMI511 Translational Biomedical Informatics


Postdoctoral Fellows:
Alisa Yurovsky

Graduate students:
Lucie Chrastecka – PhD Student, Pharmacological Sciences
Ki Oh – MSTP student, Biomedical Informatics
Luke Torre-Healy - MSTP student, Biomedical Informatics
Danielle Fassler - MSTP student, Pharmacology

Undergraduate students:
Jason Yoo
Saaya Patel
Adit Anand


Moffitt lab photo


Anuva Banwasi - Simons Summer Research Program Scholar
Rishabh Rout - Simons Summer Research Program Scholar
Ryan Kawalerski - Undergraduate, Biochemistry & AMS, now at Johns Hopkins MD/PhD
Virginia Ma - Simons Summer Research Program Scholar, now at Harvard BS